Pouch in Heart May Trigger Unexplained Strokes: Study

Researchers suspect it may allow clots to form, then travel to the brain

TUESDAY, April 7, 2015 (HealthDay News) — A pouch-like structure in the heart may be the source of some strokes that have no other known cause, a new study suggests.

This pouch in the heart’s left atrial chamber — called a left atrial septal pouch — was first discovered in 2010 by cardiologists at the University of California, Irvine.

“The cul-de-sac nature of this heart pouch may promote stagnation of the blood, forming clots that can travel into the brain and cause a stroke,” Dr. Mark Fisher, a professor of neurology and pathology and laboratory medicine, said in a UC Irvine news release.

The researchers looked at 75 stroke patients to find out if the pouch could be a source of stroke-causing blood clots.

Of the 23 patients who had a stroke of undetermined origin, 30 percent had a left atrial septal pouch, compared with only 10 percent of the 52 patients whose cause of stroke could be pinpointed.

“This finding points to a potentially important cause of strokes. The presence of this pouch could change how neurologists treat these patients and lead to new therapeutic strategies for preventing strokes,” Fisher explained.

While the researchers found an association between the pouch and unexplained strokes, it did not prove a cause-and-effect link.

The study was published recently in the journal Frontiers in Neurology.

About 80 percent of the more than 700,000 strokes that occur in the United States each year are caused by blood clots blocking brain arteries. In up to one-third of these cases, the source of the clot can’t be pinpointed, the researchers said.

More information

The U.S. National Heart, Lung, and Blood Institute has more about stroke.

— Robert Preidt


SOURCE: University of California, Irvine, news release, April 1, 2015


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